Moxifloxacin Hydrochloride IP

Eq. to Moxifloxacin 0.5% w/w

Dexamethasone Sodium Phosphate IP 0.1% w/w

Sterile Ointment Base

Dosage Form: Ophthalmic Ointment



MOXIFLOXACIN, in Moxitak-D works as an anti-bacterial

agent Floro-Quinolones exert their antibacterial effect by preventing bacterial

DNA from unwinding and duplicating. Moxifloxacin hydrochloride is a synthetic

8-methoxyfluoroquinolone with a broad spectrum anti-bacterial effect on gram

positive, gram negative and other anaerobic micro-organism. Well tolerated

with minimal ocular side effects and provides increased penetration into ocular

tissues and fluids with improved activity against Streptococci and

Staphylococci species. It has a moderate to excellent activity against clinically

relevant, gram-negative ocular pathogens.

DEXAMETHASONE - is a synthetic analog of naturally occurring

glucocorticoids (hydrocortisone and cortisone). Dexamethasone sodium

phosphate is a water soluble, inorganic ester of dexamethasone and has antiinflammatory

and immunosuppressant effects. It fulfills its function through

multiple pathways, it binds with the corticosteroid receptors and alters the

protein synthesis thus prevents the leukocyte infiltration at the site of

inflammation, interferes in the function of the mediators responsible for the

inflammatory response, suppresses the humoral immune responses and

reduction in edema or scar tissue. The anti-inflammatory actions of

dexamethasone involve phospholipase A2 inhibitory proteins which control

the biosynthesis of potent mediators of inflammation such as prostaglandins.

Indication and Usage: Bacterial Conjunctivitis (pink eye) and Bacterial

Corneal Ulcer Infection caused by susceptible strains of Staphylococcus

species. Bacterial ocular infection associated with bacterial blepharitis.

Precautions: Hypersensitivity towards any of the component in the solution.

: Apply thin strip (about 1cm) of ointment into the

affected eye(s) every 4 hours or as directed by physician.

Information to Patient: Follow the instructions that are provided by your

doctor and if the adverse effect persists, discontinue the usage and contact

your doctor immediately.

Precautions: Hypersensitivity towards any of the component in the solution.

Growth of Resistant Organisms with Prolonged


  • Avoidance of Contact Lens Wear
  • if irritations persist, discontinue the use and consult the eye doctor
  • Prolonged use may result in glaucoma
  • Defects in visual acuity and fields of vision

Adverse Effect:

  • Nausea, Diarrhea, Dizziness, blurred vision that does not go away, burning,

stinging, or itching of the eyes or eyelids.

  • Ocular hyperemia, Ocular pain and Ocular pruritus