Mode Of Action:

Gludorz is the combination of a topical carbonic anhydrase inhibitor and a topical beta- adrenergic receptor blocking agent. Together they have an additive effect on lowering intraocular pressure (IOP) when administered topically.

Timolol maleate in Gludorz Eye Drops, which is a beta blocker that enables the blocking of beta receptors present on cells of different muscles. As an ophthalmic solution it acts on the beta receptors of production causes the increase of the intra ocular pressure (resulting in Glaucoma), thus decreasing the pressure.

Dorzolamide hydrochloride, another component of Gludorz Eye Drops, when applied topically gets in the system circulation of the eye and acts as an inhibitor for carbonic anhydrase which acts as the catalyst for the reversible reaction, hydration of carbon dioxide and dehydration of carbonic acid, resulting in reduced formation of Aqueous Humor. The inhibition of the carbonic anhydrase present in the cillary processes of the eye and decreases the bicarbonate ion exchange channel.

In patients with elevated intraocular pressure suffering from Open-angle glaucoma, ocular hypertension or pseudo-exfoliative glaucoma

1. Ocular pressure should be monitored timely
2. If allergic discontinue the use and contact your eye doctor
3. Wash your hands properly before applying eye drops.
4. Do not touch the tip of the vial, because any contamination can cause inflammation in your eye.
5. Do administer while wearing contact lenses as they can absorb the solution and wear the lenses after 15 minutes of application.
6. For external use only.

Adverse Effect:

Gludorz ophthalmic solution may cause itching, blurred vision, headache or tearing in the eye.